An Qin Selected Research

Bone Resorption

12/2021	DZNep promotes mouse bone defect healing via enhancing both osteogenesis and osteoclastogenesis.
1/2021	Combination of AZD3463 and DZNep Prevents Bone Metastasis of Breast Cancer by Suppressing Akt Signaling.
12/2020	Association between the metabolome and bone mineral density in a Chinese population.
1/2020	Pregnenolone Inhibits Osteoclast Differentiation and Protects Against Lipopolysaccharide-Induced Inflammatory Bone Destruction and Ovariectomy-Induced Bone Loss.
1/2020	PP121 suppresses RANKL-Induced osteoclast formation in vitro and LPS-Induced bone resorption in vivo.
11/2019	LY411575, a potent γ-secretase inhibitor, suppresses osteoclastogenesis in vitro and LPS-induced calvarial osteolysis in vivo.
10/2019	The emerging role of IMD 0354 on bone homeostasis by suppressing osteoclastogenesis and bone resorption, but without affecting bone formation.
1/2019	Nirogacestat suppresses RANKL-Induced osteoclast formation in vitro and attenuates LPS-Induced bone resorption in vivo.
1/2019	Vx-11e protects against titanium-particle-induced osteolysis and osteoclastogenesis by supressing ERK activity.
1/2019	Psoralen accelerates bone fracture healing by activating both osteoclasts and osteoblasts.

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An Qin Research Topics

Disease

38	Bone Resorption 12/2021 - 08/2011
30	Osteolysis 01/2022 - 10/2009
17	Neoplasms (Cancer) 05/2022 - 10/2009
16	Breast Neoplasms (Breast Cancer) 03/2021 - 02/2014
15	Osteoporosis 01/2021 - 10/2009
8	Neoplasm Metastasis (Metastasis) 03/2021 - 02/2014
7	AIDS-Related Complex (ARC) 05/2021 - 01/2018
6	Osteosarcoma (Osteogenic Sarcoma) 02/2020 - 06/2014
4	Intervertebral Disc Degeneration 01/2022 - 08/2015
4	Osteoarthritis 01/2020 - 07/2014
4	Infections 01/2020 - 01/2014
4	Bone Diseases (Bone Disease) 11/2019 - 01/2017
4	Inflammation (Inflammations) 01/2019 - 02/2018
3	Metabolic Bone Diseases (Osteopenia) 01/2021 - 07/2015
3	Head and Neck Neoplasms (Head and Neck Cancer) 11/2020 - 09/2018
3	Periodontitis 09/2015 - 10/2014
3	Alveolar Bone Loss 09/2015 - 10/2014
2	Fibrosis (Cirrhosis) 01/2021 - 01/2020
2	Carcinogenesis 10/2020 - 10/2020
2	Diabetes Mellitus 01/2020 - 08/2015
2	Hypertrophy 01/2018 - 07/2014
2	Prostatic Neoplasms (Prostate Cancer) 01/2018 - 04/2015
1	Osteopetrosis 01/2021
1	Bites and Stings (Sting) 01/2021
1	Gestational Diabetes (Gestational Diabetes Mellitus) 01/2021
1	Triple Negative Breast Neoplasms 01/2021

Drug/Important Bio-Agent (IBA)

13	TitaniumIBA 01/2022 - 07/2014
7	Protons (Proton)IBA 05/2021 - 01/2018
7	Proteins (Proteins, Gene)FDA Link 10/2020 - 10/2015
7	Tartrate-Resistant Acid PhosphataseIBA 01/2020 - 07/2015
6	Messenger RNA (mRNA)IBA 01/2020 - 08/2015
6	Diphosphonates (Bisphosphonates)IBA 02/2018 - 10/2009
5	Pharmaceutical PreparationsIBA 10/2020 - 10/2017
5	LigandsIBA 01/2019 - 01/2015
4	Cathepsin KIBA 01/2020 - 01/2016
4	plumbaginIBA 04/2019 - 09/2015
4	Zoledronic Acid (Zometa)FDA Link 01/2019 - 09/2015
4	Actins (F Actin)IBA 03/2016 - 10/2014
3	Biocompatible Materials (Biomaterials)IBA 01/2022 - 03/2016
3	LipopolysaccharidesIBA 08/2020 - 02/2018
3	lycorineIBA 02/2020 - 08/2015
3	Matrix Metalloproteinases (MMPs)IBA 01/2020 - 10/2016
3	Calcitonin Receptors (Calcitonin Receptor)IBA 01/2020 - 01/2016
3	Amyloid Precursor Protein Secretases (beta-Secretase)IBA 11/2019 - 06/2014
3	Enoxacin (AT 2266)FDA Link 03/2019 - 07/2014
3	Therapeutic UsesIBA 01/2019 - 08/2014
3	andrographolideIBA 01/2019 - 02/2014
3	CytokinesIBA 01/2019 - 03/2016
2	3-deazaneplanocinIBA 12/2021 - 01/2021
2	NitrogenIBA 08/2020 - 01/2018
2	RANK LigandIBA 01/2020 - 01/2019
2	NFATC Transcription FactorsIBA 01/2020 - 01/2019
2	Mitogen-Activated Protein KinasesIBA 01/2019 - 10/2018
2	EnzymesIBA 01/2019 - 10/2016
2	Matrix Metalloproteinase 9 (Gelatinase B)IBA 01/2019 - 02/2015
2	Methotrexate (Mexate)FDA LinkGeneric 11/2018 - 10/2017
2	Alendronate (Alendronate Sodium)FDA LinkGeneric 11/2018 - 05/2016
2	artenimol (dihydroartemisinin)IBA 01/2018 - 01/2016
2	MicroRNAs (MicroRNA)IBA 03/2016 - 07/2014
2	LuciferasesIBA 12/2015 - 02/2015
2	Cisplatin (Platino)FDA LinkGeneric 12/2015 - 06/2014
2	LactonesIBA 02/2015 - 02/2014
2	DiterpenesIBA 02/2015 - 02/2014
2	Plant ExtractsIBA 01/2015 - 01/2013
1	Proteasome Endopeptidase Complex (Proteasome)IBA 01/2022
1	ferric ferrocyanide (Prussian blue)FDA Link 01/2022
1	Proprotein Convertases (Pro-Opiomelanocortin Converting Enzyme)IBA 03/2021
1	FurinIBA 03/2021
1	dehydrocostus lactoneIBA 01/2021
1	CyclinsIBA 01/2021
1	Methionine (L-Methionine)FDA Link 01/2021
1	oxymatrineIBA 01/2021
1	AZD3463IBA 01/2021
1	Long Noncoding RNAIBA 01/2021
1	Lysine (L-Lysine)FDA Link 01/2021
1	Blood Glucose (Blood Sugar)IBA 01/2021
1	Bleomycin (Blenoxane)FDA LinkGeneric 01/2021
1	Biomarkers (Surrogate Marker)IBA 12/2020
1	Metal-Organic FrameworksIBA 12/2020
1	Glucose (Dextrose)FDA LinkGeneric 10/2020
1	Tyrosine 3-Monooxygenase (Tyrosine Hydroxylase)IBA 10/2020
1	Protein Isoforms (Isoforms)IBA 10/2020
1	Tryptophan (L-Tryptophan)FDA Link 10/2020
1	N- ((2,3- dihydro- 1,4- benzodioxin- 2- yl)methyl)- 5- methoxy- 1H- indole- 3- ethanamineIBA 10/2020
1	ChitosanIBA 08/2020

Therapy/Procedure

12	Therapeutics 05/2021 - 02/2014
7	Ovariectomy (Oophorectomy) 01/2021 - 10/2014
5	Radiotherapy 01/2022 - 04/2015
5	Proton Therapy 01/2021 - 02/2018
3	Prostheses and Implants (Prosthesis) 01/2019 - 11/2014
3	Arthroplasty 03/2016 - 05/2014
3	Ligation 09/2015 - 10/2014
2	Diskectomy (Discectomy) 01/2020 - 08/2015
2	Drug Therapy (Chemotherapy) 11/2019 - 12/2015
2	Precision Medicine 04/2019 - 01/2017
2	Hip Replacement Arthroplasty (Total Hip Replacement) 01/2015 - 01/2014
2	Reoperation 10/2014 - 08/2014
1	Cyclotrons 05/2022
1	Intraperitoneal Injections 01/2021
1	Chemoradiotherapy 11/2020